A UCL study put a Tibetan lama with 54,000 hours of meditation in a brain scanner and gave him 5-MeO-DMT. The low dose didn't produce a mini-trip — it produced the same brain state as his advanced meditation practice.

A new study found that non-psilocybin/LSD psychedelics like 5-MeO-DMT are 4x more likely to trigger major life changes. Here's what the data actually says — and what it means for integration.

Last August, researchers at University College London published something remarkable in Cell Reports: the first peer-reviewed study showing exactly what happens in the human brain during a 5-MeO-DMT experience. Twenty-nine participants. High-density EEG. Rigorous methodology. The world's most powerful psychedelic, finally getting the institutional science it deserved. But this didn't come out of nowhere. For a decade before Cell Reports would touch this compound, independent

DJ Shipley spent 17 years in the Navy SEAL Teams. He did not plan to leave. When he did, everything fell apart. "I didn't know who I was anymore," he says in the Netflix documentary In Waves and War. "The mission was gone. The team was gone. The structure that gave me direction disappeared overnight." The film follows Shipley and two other former SEALs, Marcus Capone and Matty Roberts, as they confront what years of combat did to them. Depression. Rage. Isolation. Traumatic b

People who have experienced 5-MeO-DMT struggle to describe it. "The void." "Ego death." "Becoming everything and nothing." These descriptions sound mystical, possibly exaggerated. A study from University College London just captured what actually happens inside the brain during these experiences. It is unlike anything researchers have recorded before. The study Published in Cell Reports in August 2025, this research is the first to capture real-time brain activity during a 5-